Kisspeptin
Reviewed by Fat Man in the Arena · Updated March 2026
Key Takeaway
Kisspeptin is a neuropeptide that triggers the release of GnRH, playing a key role in puberty onset and reproductive hormone regulation.
How it works
Acts on the Kiss1R receptor in the hypothalamus to stimulate GnRH release, which then triggers LH and FSH secretion.
Benefits
- Stimulates natural hormone production
- Research tool for reproductive endocrinology
Side effects
- Hot flashes
- Limited human data outside research
Dosing protocol
Typical Dose
0.3-1.0 nmol/kg IV
Frequency
Research use
Primarily used in clinical research settings.
Goals
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Medical Disclaimer: This content is for informational and educational purposes only. It is not intended as medical advice or a substitute for professional medical consultation, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide protocol.