KPV
Written by Alejandro Reyes
Founder & Lead Researcher
Reviewed by Peptide Nerds Editorial · Updated April 2026
Key Takeaway
KPV is a tripeptide fragment of alpha-MSH with potent anti-inflammatory properties, primarily studied for gut inflammation and inflammatory bowel conditions.
| Type | Healing & Recovery |
| FDA Status | Research Only |
| Evidence Level | Preliminary |
| Typical Dose | 200-500 mcg daily |
| Frequency | Once daily |
| Cycle Length | 4-8 weeks |
| Key Goals | healing, inflammation |
How it works
Inhibits NF-kB inflammatory signaling pathway and reduces pro-inflammatory cytokine production.
Benefits
- Anti-inflammatory
- Gut healing potential
- Well-tolerated in reported use
Side effects
- Minimal reported side effects
- Limited human data
Dosing protocol
Typical Dose
200-500 mcg daily
Frequency
Once daily
Cycle Length
4-8 weeks
Available in oral, topical, and injectable forms.
Deeper on KPV
Full breakdowns of every part of the KPV research base.
What you will need
Basic supplies for reconstitution and subcutaneous injection.
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Bacteriostatic Water (30mL)
$8-15Required for reconstituting lyophilized peptides. 30mL is standard.
Insulin Syringes (1mL, 29ga)
$12-20 (100ct)1mL insulin syringes with 29-gauge needles for subcutaneous injection.
Alcohol Prep Pads
$5-10 (200ct)Sterile 70% isopropyl alcohol wipes for injection site prep.
Sharps Container
$8-15FDA-cleared sharps disposal container for used needles. See FDA guidance for compliant containers.
Get the KPV cheat sheet
Dosing quick-reference, key studies, and side effect management — in your inbox.
Get the KPV cheat sheet
Dosing quick-reference, key studies, and side effect management — in your inbox.
Stacks with KPV
Goals
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Medical Disclaimer: This content is for informational and educational purposes only. It is not intended as medical advice or a substitute for professional medical consultation, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide protocol.