Survodutide
Written by Alejandro Reyes
Founder & Lead Researcher
Reviewed by Peptide Nerds Editorial · Updated April 2026
Key Takeaway
Survodutide is a dual GLP-1/glucagon receptor agonist developed by Boehringer Ingelheim, currently in Phase 3 trials for obesity and metabolic liver disease.
| Type | GLP-1 / Weight Loss |
| FDA Status | Clinical Trials |
| Evidence Level | Moderate |
| Typical Dose | 0.6 mg to 4.8 mg weekly |
| Frequency | Once weekly |
| Key Goals | weight-loss, fat-loss |
How it works
Activates both GLP-1 and glucagon receptors. The glucagon component increases energy expenditure and hepatic fat oxidation while GLP-1 reduces appetite.
Benefits
- Up to 19% weight loss in Phase 2
- Significant liver fat reduction
- Potential MASH treatment
Side effects
- Nausea
- Diarrhea
- Vomiting
- Similar to other GLP-1 agonists
Dosing protocol
Typical Dose
0.6 mg to 4.8 mg weekly
Frequency
Once weekly
Phase 3 dosing not yet finalized.
Deeper on Survodutide
Full breakdowns of every part of the Survodutide research base.
What you will need
Basic supplies for reconstitution and subcutaneous injection.
This page contains affiliate links. Learn more
Bacteriostatic Water (30mL)
$8-15Required for reconstituting lyophilized peptides. 30mL is standard.
Insulin Syringes (1mL, 29ga)
$12-20 (100ct)1mL insulin syringes with 29-gauge needles for subcutaneous injection.
Alcohol Prep Pads
$5-10 (200ct)Sterile 70% isopropyl alcohol wipes for injection site prep.
Sharps Container
$8-15FDA-cleared sharps disposal container for used needles.
Get the Survodutide cheat sheet
Dosing quick-reference, key studies, and side effect management — in your inbox.
Key research
Survodutide for Obesity (Phase 2)
New England Journal of Medicine (2024) — PubMed
19.2% body weight loss at highest dose over 46 weeks.
Get the Survodutide cheat sheet
Dosing quick-reference, key studies, and side effect management — in your inbox.
Compare Survodutide
Related peptides
Get the Peptide Starter Kit (free)
Quick-start guide to GLP-1 peptides, dosing basics, and what to ask your doctor.
Medical Disclaimer: This content is for informational and educational purposes only. It is not intended as medical advice or a substitute for professional medical consultation, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide protocol.