Tirzepatide Dosage Guide
FDA Approved
FM
Reviewed by Fat Man in the Arena · Updated March 2026
Not medical advice. Dosage information is provided for educational purposes based on published research. Always consult a qualified healthcare provider before starting any protocol. Full disclaimer.
Dosage overview
| Typical dose | 2.5 mg to 15 mg weekly |
| Frequency | Once weekly subcutaneous injection |
| Cycle length | Ongoing |
Dosing notes
Start at 2.5 mg/week for 4 weeks. Titrate up in 2.5 mg increments every 4 weeks. Maximum FDA-approved dose is 15 mg/week for weight management (Zepbound).
FDA-approved indications
Tirzepatide is FDA-approved for: Type 2 diabetes (Mounjaro), chronic weight management (Zepbound).
Off-label use should only be pursued under the guidance of a licensed healthcare provider.
Important safety information
Dosage ranges listed above are based on published clinical trial protocols. Individual dosing should be determined by a qualified healthcare provider based on your specific health profile, goals, and response to treatment.
- Start at the lowest effective dose and titrate up gradually
- Monitor for side effects, especially during dose increases
- Do not exceed researched dose ranges without medical supervision
Research references
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