Dihexa
Written by Alejandro Reyes
Founder & Lead Researcher
Reviewed by Peptide Nerds Editorial · Updated April 2026
Key Takeaway
Dihexa is an extremely potent cognitive-enhancing peptide reported to be 10 million times more potent than BDNF at promoting new neural connections.
| Type | Cognitive |
| FDA Status | Research Only |
| Evidence Level | Preliminary |
| Typical Dose | 10-20 mg daily |
| Frequency | Once daily oral or subcutaneous |
| Key Goals | cognitive |
How it works
Activates hepatocyte growth factor (HGF) / c-Met receptor pathway, which promotes synaptogenesis and neuronal connectivity.
Benefits
- Extremely potent cognitive enhancement
- Promotes new synapse formation
- Memory and learning improvement
Side effects
- Very limited safety data
- Highly experimental
- Potential tumor growth concern (c-Met pathway)
Dosing protocol
Typical Dose
10-20 mg daily
Frequency
Once daily oral or subcutaneous
Highly experimental. Very limited human data. Use with extreme caution.
Deeper on Dihexa
Full breakdowns of every part of the Dihexa research base.
What you will need
Basic supplies for reconstitution and subcutaneous injection.
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Bacteriostatic Water (30mL)
$8-15Required for reconstituting lyophilized peptides. 30mL is standard.
Insulin Syringes (1mL, 29ga)
$12-20 (100ct)1mL insulin syringes with 29-gauge needles for subcutaneous injection.
Alcohol Prep Pads
$5-10 (200ct)Sterile 70% isopropyl alcohol wipes for injection site prep.
Sharps Container
$8-15FDA-cleared sharps disposal container for used needles. See FDA guidance for compliant containers.
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Dosing quick-reference, key studies, and side effect management — in your inbox.
Get the Dihexa cheat sheet
Dosing quick-reference, key studies, and side effect management — in your inbox.
Stacks with Dihexa
Goals
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Medical Disclaimer: This content is for informational and educational purposes only. It is not intended as medical advice or a substitute for professional medical consultation, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide protocol.