PeptideNerds

Mazdutide

GLP-1 / Weight LossClinical Trialsmoderate evidence
FM

Reviewed by Fat Man in the Arena · Updated March 2026

Key Takeaway

Mazdutide is a dual GLP-1/glucagon receptor agonist developed by Innovent Biologics, primarily studied in Chinese populations.

How it works

Dual GLP-1 and glucagon receptor agonism for appetite suppression and increased energy expenditure.

Benefits

  • Significant weight loss in Phase 3 trials
  • Improved metabolic markers

Side effects

  • Nausea
  • Diarrhea
  • GI side effects similar to other GLP-1 agonists

Dosing protocol

Typical Dose

3 mg to 9 mg weekly

Frequency

Once weekly

Approved in China. Not yet available in the US.

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Medical Disclaimer: This content is for informational and educational purposes only. It is not intended as medical advice or a substitute for professional medical consultation, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide protocol.