PeptideNerds

PT-141 Dosage Guide

FDA Approved
Alejandro Reyes

Written by Alejandro Reyes

Founder & Lead Researcher

PN

Reviewed by Peptide Nerds Editorial · Updated April 2026

Not medical advice. Dosage information is provided for educational purposes based on published research. Always consult a qualified healthcare provider before starting any protocol. Full disclaimer.

Dosage overview

Typical dose 1.75 mg per use
Frequency As needed, at least 45 min before activity

Dosing notes

FDA-approved as Vyleesi. Max 8 doses per month.

FDA-approved indications

PT-141 is FDA-approved for: Hypoactive sexual desire disorder in premenopausal women (Vyleesi).

Off-label use should only be pursued under the guidance of a licensed healthcare provider.

Important safety information

Dosage ranges listed above are based on published clinical trial protocols. Individual dosing should be determined by a qualified healthcare provider based on your specific health profile, goals, and response to treatment.

  • Start at the lowest effective dose and titrate up gradually
  • Monitor for side effects, especially during dose increases
  • Do not exceed researched dose ranges without medical supervision

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