Thymosin Beta-4
Written by Alejandro Reyes
Founder & Lead Researcher
Reviewed by Peptide Nerds Editorial · Updated April 2026
Key Takeaway
Thymosin Beta-4 is the full-length naturally occurring protein from which TB-500 is derived. It plays a central role in tissue repair, cell migration, and immune modulation.
| Type | Healing & Recovery |
| FDA Status | Research Only |
| Evidence Level | Preliminary |
| Typical Dose | 750 mcg to 2 mg twice weekly |
| Frequency | Twice weekly |
| Cycle Length | 4-8 weeks |
| Key Goals | healing |
How it works
Promotes actin polymerization, cell migration, and angiogenesis. Modulates inflammatory response and supports tissue regeneration.
Benefits
- Full-spectrum healing activity
- Cardiac tissue protection
- Wound healing
- Anti-inflammatory
Side effects
- Similar to TB-500
- Limited human data
Dosing protocol
Typical Dose
750 mcg to 2 mg twice weekly
Frequency
Twice weekly
Cycle Length
4-8 weeks
Less commonly used than TB-500 due to cost.
Deeper on Thymosin Beta-4
Full breakdowns of every part of the Thymosin Beta-4 research base.
What you will need
Basic supplies for reconstitution and subcutaneous injection.
This page contains affiliate links. Learn more
Bacteriostatic Water (30mL)
$8-15Required for reconstituting lyophilized peptides. 30mL is standard.
Insulin Syringes (1mL, 29ga)
$12-20 (100ct)1mL insulin syringes with 29-gauge needles for subcutaneous injection.
Alcohol Prep Pads
$5-10 (200ct)Sterile 70% isopropyl alcohol wipes for injection site prep.
Sharps Container
$8-15FDA-cleared sharps disposal container for used needles.
Get the Thymosin Beta-4 cheat sheet
Dosing quick-reference, key studies, and side effect management — in your inbox.
Get the Thymosin Beta-4 cheat sheet
Dosing quick-reference, key studies, and side effect management — in your inbox.
Compare Thymosin Beta-4
Goals
Related peptides
Looking for weight loss peptides? See our complete guide to the best peptides for weight loss or compare semaglutide vs tirzepatide .
Get the Peptide Starter Kit (free)
Quick-start guide to GLP-1 peptides, dosing basics, and what to ask your doctor.
Medical Disclaimer: This content is for informational and educational purposes only. It is not intended as medical advice or a substitute for professional medical consultation, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide protocol.