PeptideNerds

SS-31

(SS-31)
Anti-Aging Clinical Trials moderate evidence Track This Protocol
Alejandro Reyes

Written by Alejandro Reyes

Founder & Lead Researcher

PN

Reviewed by Peptide Nerds Editorial · Updated April 2026

Key Takeaway

SS-31 (Elamipretide) is a mitochondria-targeted peptide that restores mitochondrial function and has been studied in clinical trials for heart failure and mitochondrial diseases.

Quick Facts
Type Anti-Aging
FDA Status Clinical Trials
Evidence Level Moderate
Typical Dose 0.25-5 mg daily
Frequency Once daily
Key Goals anti-aging

How it works

Concentrates in the inner mitochondrial membrane, stabilizing cardiolipin and restoring electron transport chain efficiency. Reduces mitochondrial oxidative stress.

Benefits

  • Mitochondrial function restoration
  • Cardioprotective
  • Anti-aging at the cellular level

Side effects

  • Injection site reactions
  • Limited data outside clinical trials

Dosing protocol

Typical Dose

0.25-5 mg daily

Frequency

Once daily

In clinical trials for Barth syndrome and heart failure.

Deeper on SS-31

Full breakdowns of every part of the SS-31 research base.

What you will need

Basic supplies for reconstitution and subcutaneous injection.

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Stacks with SS-31

Goals

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Medical Disclaimer: This content is for informational and educational purposes only. It is not intended as medical advice or a substitute for professional medical consultation, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide protocol.