PeptideNerds

SS-31

(SS-31)
Anti-AgingClinical Trialsmoderate evidence
FM

Reviewed by Fat Man in the Arena · Updated March 2026

Key Takeaway

SS-31 (Elamipretide) is a mitochondria-targeted peptide that restores mitochondrial function and has been studied in clinical trials for heart failure and mitochondrial diseases.

How it works

Concentrates in the inner mitochondrial membrane, stabilizing cardiolipin and restoring electron transport chain efficiency. Reduces mitochondrial oxidative stress.

Benefits

  • Mitochondrial function restoration
  • Cardioprotective
  • Anti-aging at the cellular level

Side effects

  • Injection site reactions
  • Limited data outside clinical trials

Dosing protocol

Typical Dose

0.25-5 mg daily

Frequency

Once daily

In clinical trials for Barth syndrome and heart failure.

Goals

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Medical Disclaimer: This content is for informational and educational purposes only. It is not intended as medical advice or a substitute for professional medical consultation, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide protocol.