The Anti-Aging Stack
Targets three core aging pathways simultaneously: epitalon activates telomerase to protect chromosomal integrity, GHK-Cu resets gene expression patterns toward a younger state, and SS-31 repairs mitochondrial function at the cellular level.
Difficulty
advanced
Est. Cost
$300-600
Duration
10-20 days (epitalon cycle), 3-6 months (GHK-Cu + SS-31)
Peptides
3 compounds
Protocol
| Peptide | Dose | Frequency | Timing | Role |
|---|---|---|---|---|
| Epitalon | 5-10mg | Once daily for 10-20 days | Evening | Telomerase activation for telomere extension and pineal gland support |
| GHK-Cu | 1-2mg SubQ or topical serum | Once daily | Morning | Gene modulation (resets 4,000+ genes), collagen synthesis, wound healing |
| SS-31 | 0.5-1mg | Once daily | Morning | Mitochondrial inner membrane stabilization, reduces oxidative stress |
Notes
Each compound targets a different hallmark of aging. Epitalon is cycled short-term (10-20 days, then 4-6 months off) because it activates telomerase which the body naturally downregulates. GHK-Cu and SS-31 can be run longer-term. GHK-Cu has over 4,000 gene expression studies showing it shifts gene activity toward patterns seen in younger tissue. SS-31 (elamipretide) is in clinical trials for mitochondrial diseases and targets the cardiolipin in mitochondrial membranes. Blood work before and during protocol recommended. This stack pairs well with NAD+ precursors and a comprehensive longevity lifestyle protocol.
Related goals
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GHK-Cu vs Epitalon: Copper Peptide vs Telomerase Activator
GHK-Cu vs BPC-157: Anti-Aging vs Healing Peptides
BPC-157 vs GHK-Cu: Healing vs Anti-Aging Peptide Showdown
BPC-157 vs GHK-Cu vs TB-500: The Complete Healing Peptide Comparison
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Written by Alejandro Reyes
Founder & Lead Researcher
Reviewed by Peptide Nerds Editorial · Updated March 2026
Medical Disclaimer: Peptide stacks are not FDA-approved protocols. This information is for educational purposes only. Consult a qualified healthcare provider before combining any peptides.