PeptideNerds

GH Optimization Stack

Growth hormone secretagogue stack combining GHRP and GHRH for synergistic GH release without exogenous HGH.

Difficulty

intermediate

Est. Cost

$100-250

Duration

3-6 months

Peptides

2 compounds

Protocol

PeptideDoseFrequencyTimingRole
Ipamorelin200-300mcg2-3x dailyMorning, post-workout, and before bedGHRP — stimulates clean GH pulse via ghrelin receptor
CJC-1295100-200mcg (no DAC) or 2mg (with DAC)2-3x daily (no DAC) or 2x/week (with DAC)Same timing as ipamorelinGHRH analog — amplifies and extends GH release

Notes

Take on empty stomach (no food 2 hours before, 30 min after). The pre-bed dose is most important — aligns with natural GH pulse during deep sleep. CJC-1295 with DAC is more convenient (less frequent dosing) but some prefer without DAC for more natural pulsing. Avoid taking with carbs or fats as they blunt GH release.

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Reviewed by Fat Man in the Arena · Updated March 2026

Medical Disclaimer: Peptide stacks are not FDA-approved protocols. This information is for educational purposes only. Consult a qualified healthcare provider before combining any peptides.