GH Optimization Stack
Growth hormone secretagogue stack combining GHRP and GHRH for synergistic GH release without exogenous HGH.
Difficulty
intermediate
Est. Cost
$100-250
Duration
3-6 months
Peptides
2 compounds
Protocol
| Peptide | Dose | Frequency | Timing | Role |
|---|---|---|---|---|
| Ipamorelin | 200-300mcg | 2-3x daily | Morning, post-workout, and before bed | GHRP — stimulates clean GH pulse via ghrelin receptor |
| CJC-1295 | 100-200mcg (no DAC) or 2mg (with DAC) | 2-3x daily (no DAC) or 2x/week (with DAC) | Same timing as ipamorelin | GHRH analog — amplifies and extends GH release |
Notes
Take on empty stomach (no food 2 hours before, 30 min after). The pre-bed dose is most important — aligns with natural GH pulse during deep sleep. CJC-1295 with DAC is more convenient (less frequent dosing) but some prefer without DAC for more natural pulsing. Avoid taking with carbs or fats as they blunt GH release.
Related goals
Related Comparisons
Ipamorelin vs CJC-1295: Growth Hormone Peptides Compared
Ipamorelin + CJC-1295 vs MK-677: GH Peptides vs Oral Secretagogue
Tesamorelin vs Ipamorelin: Which GH Peptide Is Right for You?
Sermorelin vs Ipamorelin: Two Paths to Growth Hormone Release
GHRP-2 vs GHRP-6 vs Ipamorelin: Which GHRP Is Best?
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Written by Alejandro Reyes
Founder & Lead Researcher
Reviewed by Peptide Nerds Editorial · Updated April 2026
Medical Disclaimer: Peptide stacks are not FDA-approved protocols. This information is for educational purposes only. Consult a qualified healthcare provider before combining any peptides.