Tesamorelin
Reviewed by Fat Man in the Arena · Updated March 2026
Key Takeaway
Tesamorelin is a GHRH analog FDA-approved for reducing excess abdominal fat in HIV-associated lipodystrophy. It is the only FDA-approved GH secretagogue currently available.
How it works
Stimulates pituitary GH release via GHRH receptor activation, specifically reducing visceral adipose tissue.
Benefits
- FDA-approved for lipodystrophy
- Reduces visceral fat
- Improves body composition
- Cognitive benefits reported
Side effects
- Injection site reactions
- Joint pain
- Fluid retention
- Muscle pain
Dosing protocol
Typical Dose
2 mg daily
Frequency
Once daily
FDA-approved dose for lipodystrophy.
FDA status
FDA Approved for: HIV-associated lipodystrophy (Egrifta)
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Medical Disclaimer: This content is for informational and educational purposes only. It is not intended as medical advice or a substitute for professional medical consultation, diagnosis, or treatment. Always consult a qualified healthcare provider before starting any peptide protocol.